DMT or dimethyltryptamine, a natural psychedelic substance

DMT or dimethyltryptamine, a natural psychedelic substance

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DMT (dimethyltryptamine) is a hallucinogenic compound It is found naturally in a variety of plant species and occurs endogenously in the human brain.

As a drug, this substance can be consumed as an infusion of Amazonian psychedelic plants known as ayahuasca, can be inhaled or injected in the form of synthetic white crystalline powder.

DMT does not seem to produce tolerance and dependence in the same way as other drugs like the cocaine, heroin or alcohol. However, there are numerous adverse effects associated with the use and abuse of DMT.


  • 1 What is the DMT
  • 2 Effects of DMT
  • 3 Possible side effects of DMT
  • 4 Long-term effects of DMT abuse
  • 5 DMT addiction

What is the DMT?

DMT is a naturally occurring psychedelic substance of the tryptamine class, which produces unique psychedelic effects of great power but ephemeral when administered.

Depending on the dose and method of administration, the effects of DMT can vary from mild psychedelic states to powerful immersive experiences that are often described as the shift of consciousness in which users are placed in a subjective state where they can experience and explore ineffable spiritual states or alternative dimensions.

DMT is present in more than 65 species of plants and has been identified as a normal constituent of human metabolism and a endogenous neurotransmitter in certain rodents. It is also known that its presence is widespread throughout the plant kingdom. Although several theories have been postulated, their neurobiological function has not yet been determined.

Currently, DMT is known as an extremely powerful psychedelic substance that, when vaporized or smoked, produces short-lived effects with a very fast start which is sometimes described as a "roller coaster at an incredibly high speed." When ingested in combination with an MAOI or RIMA agent, it becomes active orally and of a significantly more lasting, immersive and interactive nature: this combination is known as ayahuasca. Ayahuasca beers have been traditionally used in South America since at least around the year 1500.

Unlike most banned substances, the scientific community does not consider DMT to be addictive or toxic. However, unpredictable adverse reactions such as uncontrollable anxiety, delusions and psychosis, particularly among those predisposed to mental disorders. While these negative reactions or "bad trips" can often be attributed to user inexperience or improper substance preparation, it is known that they also occur spontaneously even among highly experienced users.

DMT effects

DMT is consumed by people looking for a psychedelic "trip" similar to those produced by the LSD or psilocybin. Many drug users choose DMT as an alternative to LSD because the duration of the trip is much shorter, with a duration of approximately 30 to 45 minutes instead of several hours, as is the case of LSD.

This substance has a rapid onset and the effects are felt almost immediately.

Physical effects

  • Feelings of intense joy and physical euphoria.
  • Changes in the feeling of gravity: at high doses, physical sensations of being thrown over great distances at incredible speeds may appear.
  • Changes in visual perception: color improvement, with intensified brightness and colors, greater visual acuity and pattern recognition.
  • Changes in auditory perception: improvements in auditory acuity.
  • Spatial disorientation
  • Changes in the perception of body shape.
  • Sickness.
  • Pupillary dilation
  • Incrise of cardiac frecuency.
  • Temperature regulation suppression.
  • Seizures: This is a very rare effect, but it is believed to occur in those who are predisposed to them, especially in physically demanding conditions, such as being dehydrated, fatigued or malnourished.

Cognitive effects

  • Anxiety.
  • Hallucinations
  • Feeling of being out of the body
  • Cognitive euphoria
  • Feelings of imminent death.
  • Increased appreciation of music.
  • Memory loss.
  • Full attention: This effect tends to occur after the experience is over and the individual has returned to the ordinary waking consciousness, but with a sense of presence and sensitivity towards the internal and external sensations of the environment.
  • Multiple thought flows: This effect tends to manifest itself in a much more chaotic way, in conjunction with the feeling of cognitive overload.
  • Feeling of rejuvenation: This effect tends to occur after the experience is over, often in variants of near-death experience that an experience with DMT can generate.
  • Time distortion: This effect is a very prominent aspect of the DMT experience, which only tends to last less than 15 minutes.
  • Feeling of death

Bad trips

While the DMT trip may be psychologically enjoyable for some users, others may experience what is commonly known as a "bad trip."

A bad trip may consist of the following symptoms:

  • Feelings of loss of control.
  • Disorientation or confusion.
  • Negative emotions such as fear, anxiety, pain, anger or agitation.
  • Afraid to go crazy
  • Violent or unpleasant images or sounds.
  • Reliving painful memories or traumas.
  • Fear of death

Possible side effects of DMT

  • Dilated pupils.
  • Rapid involuntary eye movement.
  • Incrise of cardiac frecuency.
  • Arterial hypertension.
  • Coordination problems
  • Dizziness.
  • Nausea and vomiting (usually when taken in oral forms such as ayahuasca).
  • Eat and / or respiratory arrest (reported in high doses).
  • Fear of death

Long-term effects of DMT abuse

It seems that the greatest risks of long-term use of DMT are the psychological effects, since its consumption puts the individual in risk of developing psychosis and experiencing recurring memories and hallucinations. Flashbacks can occur frequently and spontaneously. Some users may experience retrospective scenes of medication experiences months or even years after use. They can also cause a sensation of experiencing the hallucinogenic trip again, resulting in a resurgence of visual or auditory hallucinations or a revival of traumatic memories or experiences.

DMT addiction

While DMT does not cause physical dependence, some people can abuse the drug to the point that they experience numerous problems as a result. This may be especially true in cases of abuse of various substances, where the consumer combines DMT with other psychoactive substances. A pattern of problematic hallucinogen use usually has the following symptoms:

  • Consume more DMT than desired.
  • Attempt to control or stop the use of DMT without success.
  • Invest a lot of time and energy to obtain and consume DMT or recover from its effects.
  • Ignore personal and professional obligations.
  • Continue consumption of DMT despite increasing interpersonal, social or physical / mental health problems.
  • Give up other habits or hobbies.


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